CMTM8 rabbit pAb

CAT: 0855-ES8424-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES8424-01Size:50 µL
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Background
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene acts as a tumor suppressor, and plays a role in regulating the migration of tumor cells. The encoded protein is thought to function as a a negative regulator of epidermal growth factor-induced signaling. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]
Description
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene acts as a tumor suppressor, and plays a role in regulating the migration of tumor cells. The encoded protein is thought to function as a a negative regulator of epidermal growth factor-induced signaling. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016],
Product Name Alternative
CMTM8; CKLFSF8; CKLF-like MARVEL transmembrane domain-containing protein 8; Chemokine-like factor superfamily member 8
UniProt
Q8IZV2
Swiss Prot
Q8IZV2
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human CMTM8. AA range:101-150
Target
CMTM8
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
20kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
20kD
Fragment
IgG
Subcellular Location
[Isoform 1]: Membrane; Multi-pass membrane protein.; [Isoform 2]: Cytoplasm. Nucleus.
Other Product Names
CMTM8; CKLFSF8; CKLF-like MARVEL transmembrane domain-containing protein 8; Chemokine-like factor superfamily member 8
Gene ID (Human)
152189

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