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CD296 rabbit pAb

CAT: 0855-ES8396-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES8396-02Size:100 µL
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Background
ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. The amino acid sequence consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI) -anchored proteins. This gene was previously designated ART2. [provided by RefSeq, Jul 2008]
Description
ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. The amino acid sequence consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins. This gene was previously designated ART2. [provided by RefSeq, Jul 2008],
Product Name Alternative
ART1; GPI-linked NAD (P) (+) --arginine ADP-ribosyltransferase 1; ADP-ribosyltransferase C2 and C3 toxin-like 1; ARTC1; Mono (ADP-ribosyl) transferase 1; CD296
UniProt
P52961
Swiss Prot
P52961
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human ART1. AA range:51-100
Target
CD296
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
37kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
37kD
Fragment
IgG
Subcellular Location
Sarcoplasmic reticulum membrane; Lipid-anchor, GPI-anchor.
Other Product Names
ART1; GPI-linked NAD (P) (+) --arginine ADP-ribosyltransferase 1; ADP-ribosyltransferase C2 and C3 toxin-like 1; ARTC1; Mono (ADP-ribosyl) transferase 1; CD296
Gene ID (Human)
417

UniProtKB · P52961

GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1

NAR1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P52961
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ART1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.4.2.31
Processing
Precursor
Secondary accessions
Q6NTD2, Q96KT9
Protein keywords

PTM

Disulfide bondGlycoproteinGPI-anchorLipoprotein

Molecular function

GlycosyltransferaseNucleotidyltransferaseTransferase

Cellular component

MembraneSarcoplasmic reticulum

Ligand

NADNADP

Technical term

Proteomics identificationReference proteome

Domain

Signal

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