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Thrombospondin 2 rabbit pAb

CAT: 0855-ES8379-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES8379-01Size:50 µL
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Background
Thrombospondin 2 (THBS2) Homo sapiens The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown to function as a potent inhibitor of tumor growth and angiogenesis. Studies of the mouse counterpart suggest that this protein may modulate the cell surface properties of mesenchymal cells and be involved in cell adhesion and migration. [provided by RefSeq, Jul 2008]
Description
Thrombospondin 2 (THBS2) Homo sapiens The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown to function as a potent inhibitor of tumor growth and angiogenesis. Studies of the mouse counterpart suggest that this protein may modulate the cell surface properties of mesenchymal cells and be involved in cell adhesion and migration. [provided by RefSeq, Jul 2008],
Product Name Alternative
THBS2; TSP2; Thrombospondin-2
UniProt
P35442
Swiss Prot
P35442
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the C-terminal region of human THBS2. AA range:1000-1050
Target
Thrombospondin 2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
130kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
130kD
Fragment
IgG
Subcellular Location
Extracellular region, basement membrane, extracellular matrix, platelet alpha granule
Other Product Names
THBS2; TSP2; Thrombospondin-2
Gene ID (Human)
7058

UniProtKB · P35442

Thrombospondin-2

TSP2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P35442
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
THBS2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A6H8N1, A7E232, Q5RI52
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Ligand

Calcium

Biological process

Cell adhesion

Disease

Disease variantEhlers-Danlos syndrome

PTM

Disulfide bondGlycoprotein

Domain

EGF-like domainRepeatSignal

Molecular function

Heparin-binding

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