APP-BP2 rabbit pAb

• Background:

  The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

• Description:

  The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],

• UniProt:

  Q92624

• Swiss Prot:

  Q92624

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Synthesized peptide derived from APP-BP2 . at AA range: 390-470

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

• Molecular Weight:

  67kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  67kD

• Fragment:

  IgG

• Subcellular Location:

  Nucleus . Cytoplasm, cytoskeleton . Membrane ; Peripheral membrane protein . Associated with membranes and microtubules. .

• Other Product Names:

  APPBP2; KIAA0228; PAT1; Amyloid protein-binding protein 2; Amyloid beta precursor protein-binding protein 2; APP-BP2; Protein interacting with APP tail 1

• Gene ID (Human):

  10513