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Tensin-2 rabbit pAb

CAT: 0855-ES8345-01Size: 50 µLDry Ice: NoHazardous: No
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Background
The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in regulating cell migration. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
Description
The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in regulating cell migration. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008],
Product Name Alternative
TENC1; KIAA1075; TNS2; Tensin-like C1 domain-containing phosphatase; C1 domain-containing phosphatase and tensin homolog; C1-TEN; Tensin-2
UniProt
Q63HR2
Swiss Prot
Q63HR2
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human Tensin-2. AA range:439-488
Target
Tensin-2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
125kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
125kD
Fragment
IgG
Subcellular Location
Cell junction, focal adhesion . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Detected at the end of actin stress fibers. Detected in cytoplasmic punctate bodies (PubMed:22019427) . .
Other Product Names
TENC1; KIAA1075; TNS2; Tensin-like C1 domain-containing phosphatase; C1 domain-containing phosphatase and tensin homolog; C1-TEN; Tensin-2
Gene ID (Human)
23371

UniProtKB · Q63HR2

Tensin-2

TENS2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q63HR2
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TNS2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.1.3.48
Processing
—
Secondary accessions
A2VDF2, A2VDF3, A2VDI8, A5PKY4, Q2NL80, Q76MW6, Q7Z5T9, Q8NFF9, Q8NFG0, Q96P25, Q9NT29, Q9UPS7
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell junctionCell membraneCytoplasmMembrane

Molecular function

HydrolaseProtein phosphatase

Ligand

Lipid-bindingMetal-bindingZinc

PTM

MethylationPhosphoproteinUbl conjugation

Domain

SH2 domainZinc-finger

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