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CEP350 rabbit pAb

CAT: 0855-ES8113-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES8113-01Size:50 µL
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Background
Centrosomal protein 350 (CEP350) Homo sapiens The product of this gene is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. The encoded protein primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. The encoded protein directly interacts with another large centrosomal protein and is required to anchor microtubules at the centrosome. It is also implicated in the regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Description
Centrosomal protein 350 (CEP350) Homo sapiens The product of this gene is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. The encoded protein primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. The encoded protein directly interacts with another large Centrosomal protein and is required to anchor microtubules at the centrosome. It is also implicated in the regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008],
UniProt
Q5VT06
Swiss Prot
Q5VT06
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human CEP35. AA range:671-720
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cytoplasm, cytoskeleton, cilium basal body . Associated with mitotic spindles (PubMed:16314388) . Nuclear, in discrete foci. Associated with intermediate filaments (PubMed:15615782) . Also present in the pericentrosomal area (PubMed:17878239) . Localizes on both mother and daughter centrioles. Localizes to an axial position on the mother centriole (PubMed:28625565) . Localizes to the distal end of the centriole on the subdistal appendage region (PubMed:28659385) . .
Other Product Names
CEP350; CAP350; KIAA0480; GM133; Centrosome-associated protein 350; Cep350; Centrosome-associated protein of 350 kDa
Gene ID (Human)
9857

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