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RN-tre rabbit pAb

CAT: 0855-ES8089-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES8089-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Acts as a GTPase-activating protein for RAB5A. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 1 Rab-GAP TBC domain., subunit:Interacts with EPS8., tissue specificity:Widely expressed.
Description
Function: Acts as a GTPase-activating protein for RAB5A. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Contains 1 Rab-GAP TBC domain. subunit: Interacts with EPS8. tissue specificity: Widely expressed.
UniProt
Q92738
Swiss Prot
Q92738
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human USP6NL. AA range:451-500
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Golgi apparatus. Cytoplasmic vesicle.
Other Product Names
USP6NL; KIAA0019; USP6 N-terminal-like protein; Related to the N-terminus of tre; RN-tre
Gene ID (Human)
9712