CD28 (phospho Tyr218) rabbit pAb

• Background:

  The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]

• Description:

  The protein encoded by this gene is essential for T-cell proliferation and survival, Cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011],

• Synonyms:

  CD28; T-cell-specific surface glycoprotein CD28; TP44; CD antigen CD28

• Gene ID:

  940

• UniProt:

  P10747

• Cellular Locus:

  Membrane; Single-pass type I membrane protein.; [Isoform 3]: Cell surface.

• Host:

  Rabbit

• Species Reactivity:

  Human

• Reactivity:

  Human

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human CD28 around the phosphorylation site of Tyr218. AA range:171-220

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, ELISA

• Validated Applications:

  WB, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

• Molecular Weight:

  45kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  45 kD

• Subcellular Location:

  Membrane; Single-pass type I membrane protein.; [Isoform 3]: Cell surface .

• Other Product Names:

  CD28; T-cell-specific surface glycoprotein CD28; TP44; CD antigen CD28

• Gene ID (Human):

  940

• SwissProt (Human):

  P10747