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SREC-II rabbit pAb

CAT: 0855-ES7962-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES7962-01Size:50 µL
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Background
The protein encoded by this gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL) . This protein has only little activity of internalizing modified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. The association of this protein with SCARF1 is suppressed by the presence of scavenger ligands. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Description
The protein encoded by this gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). This protein has only little activity of internalizing modified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. The association of this protein with SCARF1 is suppressed by the presence of scavenger ligands. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],
UniProt
Q96GP6
Swiss Prot
Q96GP6
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human SCARF2. AA range:677-726
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Membrane ; Single-pass type I membrane protein .
Other Product Names
SCARF2; SREC2; SREPCR; Scavenger receptor class F member 2; SRECRP-1; Scavenger receptor expressed by endothelial cells 2 protein; SREC-II
Gene ID (Human)
91179

UniProtKB · Q96GP6

Scavenger receptor class F member 2

SREC2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96GP6
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SCARF2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
E5RFB8, Q58A83, Q8IXF3, Q9BW74
Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

Cell adhesion

Disease

Disease variant

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

EGF-like domainRepeatSignalTransmembraneTransmembrane helix

Cellular component

Membrane

Technical term

Proteomics identificationReference proteome

Molecular function

Receptor

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APRab18266-01SREC-II Rabbit Polyclonal Antibody
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APRab18265-01SREC Rabbit Polyclonal Antibody
APA1715-01SREC-I Rabbit pAb
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GTR18407431-01SREC-I Recombinant Rabbit mAb
E56G3121SREC-I Rabbit Monoclonal Antibody
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