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CPLA2-γ rabbit pAb

CAT: 0855-ES7831-01Size: 50 µLDry Ice: NoHazardous: No
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Background
This gene encodes a protein which is a member of the phospholipase A2 enzyme family which hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids, both of which serve as precursors in the production of signaling molecules. The encoded protein has been shown to be a calcium-independent and membrane bound enzyme. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]
Description
This gene encodes a protein which is a member of the phospholipase A2 enzyme family which hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids, both of which serve as precursors in the production of signaling molecules. The encoded protein has been shown to be a calcium-independent and membrane bound enzyme. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009],
Product Name Alternative
PLA2G4C; Cytosolic phospholipase A2 gamma; cPLA2-gamma; Phospholipase A2 group IVC
UniProt
Q9UP65
Swiss Prot
Q9UP65
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human PLA2G4C. AA range:301-350
Target
CPLA2-γ
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
70kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
70kD
Fragment
IgG
Subcellular Location
Cell membrane ; Lipid-anchor . Endoplasmic reticulum membrane ; Lipid-anchor. Mitochondrion membrane ; Lipid-anchor. Lipid droplet . Translocates from endoplasmic reticulum to lipid droplets in response to oleate. .
Other Product Names
PLA2G4C; Cytosolic phospholipase A2 gamma; cPLA2-gamma; Phospholipase A2 group IVC
Gene ID (Human)
8605

UniProtKB · Q9UP65

Cytosolic phospholipase A2 gamma

PA24C_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UP65
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PLA2G4C
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
cPLA2-gamma
EC number
3.1.1.4
Processing
Precursor
Secondary accessions
B2RB71, B4DI40, O75457, Q6IBI8, Q9UG68
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneEndoplasmic reticulumLipid dropletMembraneMitochondrion

Biological process

Host-virus interactionLipid metabolismPhospholipid metabolism

Molecular function

HydrolaseTransferase

PTM

LipoproteinMethylationPhosphoproteinPrenylation

Technical term

Proteomics identificationReference proteome