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Rab 1B rabbit pAb

CAT: 0855-ES7653-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES7653-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al., 1997 [PubMed 9030196]; Alvarez et al., 2003 [PubMed 12802079]) .[supplied by OMIM, Jan 2009]
Description
Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al. 1997 [PubMed 9030196]; Alvarez et al. 2003 [PubMed 12802079]). [supplied by OMIM, Jan 2009],
Product Name Alternative
RAB1B; Ras-related protein Rab-1B
UniProt
Q9H0U4
Swiss Prot
Q9H0U4
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from Rab 1B . at AA range: 50-130
Target
Rab 1B
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Buffer
-20°C/1 year
Molecular Weight
22kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
22kD
Fragment
IgG
Subcellular Location
Cytoplasm . Membrane ; Lipid-anchor ; Cytoplasmic side . Preautophagosomal structure membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasm, perinuclear region . Targeted by REP1 to membranes of specific subcellular compartments including endoplasmic reticulum, Golgi apparatus, and intermediate vesicles between these two compartments (PubMed:11389151) . In the GDP-form, colocalizes with GDI in the cytoplasm (PubMed:11389151) . Co-localizes with MTMR6 to the endoplasmic reticulum-Golgi intermediate compartment and to the peri-Golgi region (By similarity) . .
Other Product Names
RAB1B; Ras-related protein Rab-1B
Gene ID (Human)
81876

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