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Rab 38 rabbit pAb

CAT: 0855-ES5378-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES5378-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1., PTM:Although at least one in vitro system can process and methylate the prenylated C-terminal, in an in vitro system that normally express Rab-38 and in vivo the prenylated C-terminal is not proteolytically processed and not methylated., similarity:Belongs to the small GTPase superfamily. Rab family., tissue specificity:Expressed in melanocytes.
Description
Function: May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1. PTM: Although at least one in vitro system can process and methylate the prenylated C-terminal, in an in vitro system that normally express Rab-38 and in vivo the prenylated C-terminal is not proteolytically processed and not methylated. similarity: Belongs to the small GTPase superfamily. Rab family. tissue specificity: Expressed in melanocytes.
UniProt
P57729
Swiss Prot
P57729
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human RAB38. AA range:80-129
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Molecular Weight
26kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
26kD
Fragment
IgG
Subcellular Location
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome membrane . Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211) . The BLOC-3 complex, a heterodimer of HPS1 and HPS4 promotes its membrane localization (PubMed:23084991) . .
Other Product Names
RAB38; Ras-related protein Rab-38; Melanoma antigen NY-MEL-1
Gene ID (Human)
23682

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