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CHSY2 rabbit pAb

CAT: 0855-ES7583-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES7583-01Size:50 µL
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Background
Catalytic activity:UDP-alpha-D-glucuronate + N-acetyl-beta-D-galactosaminyl- (1->4) -beta-D-glucuronosyl-proteoglycan = UDP + beta-D-glucuronosyl- (1->3) -N-acetyl-beta-D-galactosaminyl- (1->4) -beta-D-glucuronosyl-proteoglycan., catalytic activity:UDP-N-acetyl-D-galactosamine + beta-D-glucuronosyl- (1->3) -N-acetyl-beta-D-galactosaminyl-proteoglycan = UDP + N-acetyl-beta-D-galactosaminyl- (1->4) -beta-D-glucuronosyl- (1->3) -N-acetyl-beta-D-galactosaminyl-proteoglycan., cofactor:Divalent cations. Highest activities are measured with manganese. Can also utilize cobalt., function:Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer., online information:GlycoGene database, PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the chondroitin N-acetylgalactosaminyltransferase family., subunit:Binds CHSY1., tissue specificity:Ubiquitous. Highly expressed in pancreas, ovary, brain, heart, skeletal muscle, colon, kidney, liver, stomach, small intestine and placenta.
Description
Catalytic activity: UDP-alpha-D-glucuronate + N-acetyl-beta-D-galactosaminyl- (1->4)-beta-D-glucuronosyl-proteoglycan = UDP + beta-D-glucuronosyl- (1->3)-N-acetyl-beta-D-galactosaminyl- (1->4)-beta-D-glucuronosyl-proteoglycan. Catalytic activity: UDP-N-acetyl-D-galactosamine + beta-D-glucuronosyl- (1->3)-N-acetyl-beta-D-galactosaminyl-proteoglycan = UDP + N-acetyl-beta-D-galactosaminyl- (1->4)-beta-D-glucuronosyl- (1->3)-N-acetyl-beta-D-galactosaminyl-proteoglycan. Cofactor: Divalent cations. Highest activities are measured with manganese. Can also utilize cobalt. function: Has both beta-1, 3-glucuronic acid and beta-1, 4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. online information: GlycoGene database, PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Belongs to the chondroitin N-acetylgalactosaminyltransferase family. subunit: Binds CHSY1. tissue specificity: Ubiquitous. Highly expressed in pancreas, ovary, brain, heart, skeletal muscle, colon, kidney, liver, stomach, small intestine and placenta.
Product Name Alternative
CHPF; CSS2; Chondroitin sulfate synthase 2; Chondroitin glucuronyltransferase 2; Chondroitin-polymerizing factor; ChPF; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II; N-acetylgalactosaminyl-pro
UniProt
Q8IZ52
Swiss Prot
Q8IZ52
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human CHSY2. AA range:631-680
Target
CHSY2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
85kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
85kD
Fragment
IgG
Subcellular Location
[Isoform 1]: Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein . Cytoplasm, cytosol .; [Isoform 3]: Cytoplasm, cytosol . Mitochondrion .; [Isoform 2]: Mitochondrion matrix .
Other Product Names
CHPF; CSS2; Chondroitin sulfate synthase 2; Chondroitin glucuronyltransferase 2; Chondroitin-polymerizing factor; ChPF; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II; N-acetylgalactosaminyl-pro
Gene ID (Human)
79586

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