ZnT-4 rabbit pAb
CAT:
855-ES7552-02
Size:
100 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ZnT-4 rabbit pAb
- Description: Zinc is the second most abundant trace metal in the human body. It is an essential element, serving both a structural role, as in the formation of zinc fingers in DNA-binding proteins, and a catalytic role in metalloenzymes, such as pancreatic carboxypeptidases (e. g. MIM 114852), alkaline phosphatases (e. g. MIM 171760), various dehydrogenases, and superoxide dismutases (e. g. MIM 147450). SLC30A4, or ZNT4, belongs to the ZNT family of zinc transporters. ZNTs are involved in transporting zinc out of the cytoplasm and have similar structures, consisting of 6 transmembrane domains and a histidine-rich cytoplasmic loop (Huang and Gitschier, 1997 [PubMed 9354792]). [supplied by OMIM, Mar 2008],
- Synonyms: SLC30A4; ZNT4; Zinc transporter 4; ZnT-4; Solute carrier family 30 member 4
- Gene ID: 7782
- UniProt: O14863
- Cellular Locus: Endosome membrane ; Multi-pass membrane protein. Late endosome membrane ; Multi-pass membrane protein. Lysosome membrane ; Multi-pass membrane protein.
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: The antiserum was produced against synthesized peptide derived from human SLC30A4. AA range:71-120
- Clonality: Polyclonal
- Validated Applications: WB, IHC, IF, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
- Molecular Weight: 47kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.