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VRK2 rabbit pAb

CAT: 0855-ES7511-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES7511-01Size:50 µL
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Background
Vaccinia related kinase 2 (VRK2) Homo sapiens This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in this gene have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity. [provided by RefSeq, Jan 2014]
Description
Vaccinia related kinase 2 (VRK2) Homo sapiens This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in this gene have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity. [provided by RefSeq, Jan 2014],
Product Name Alternative
VRK2; Serine/threonine-protein kinase VRK2; Vaccinia-related kinase 2
UniProt
Q86Y07
Swiss Prot
Q86Y07
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human VRK2. AA range:171-220
Target
VRK2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
55kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
55kD
Fragment
IgG
Subcellular Location
[Isoform 1]: Cytoplasm . Endoplasmic reticulum membrane ; Single-pass type IV membrane protein . Mitochondrion membrane ; Single-pass type IV membrane protein . Nucleus envelope .; [Isoform 2]: Cytoplasm . Nucleus .
Other Product Names
VRK2; Serine/threonine-protein kinase VRK2; Vaccinia-related kinase 2
Gene ID (Human)
7444