Products for Research Use Only
RegisterLogin

Tenascin-X rabbit pAb

CAT: 0855-ES7410-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES7410-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Description
This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
UniProt
P22105
Swiss Prot
P22105
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human TNXB. AA range:1761-1810
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Secreted, extracellular space, extracellular matrix.
Other Product Names
TNXB; HXBL; TNX; TNXB1; TNXB2; XB; Tenascin-X; TN-X; Hexabrachion-like protein
Gene ID (Human)
7148

UniProtKB · P22105

Tenascin-X

TENX_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P22105
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TNXB
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
TN-X
EC number
—
Processing
Precursor
Secondary accessions
P78530, P78531, Q08424, Q08AM0, Q08AM1, Q59GU7, Q5SQD3, Q5ST74, Q7L8Q4, Q8N4R1, Q9NPK9, Q9UC10, Q9UC11, Q9UC12, Q9UC13, Q9UMG7
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cell adhesion

Domain

Coiled coilEGF-like domainRepeatSignal

Disease

Disease variantEhlers-Danlos syndrome

PTM

Disulfide bondGlycoprotein

Cellular component

Extracellular matrixSecreted

Related Products

CatalogName
ES8665-01Tenascin-R rabbit pAb
ES4278-01Tenascin-C rabbit pAb
ELK2687-01Human TNX (Tenascin X) ELISA Kit
ES1659-01Annexin X rabbit pAb
ES1761-01Bcl-x rabbit pAb
ES5822-01Synaptotagmin X rabbit pAb
ES3209-01PIG-X rabbit pAb
ES8674-01Integrin αX rabbit pAb
ES2525-01Histone H2A.X rabbit pAb
ES1059-01Cleaved-Factor X/ Factor X LC (A41) rabbit pAb

Alternative Products

CatalogName
E2861165Tenascin X Rabbit pAb
GTR18114653-01Tenascin X Rabbit Polyclonal Antibody
AG3434Tenascin X Rabbit Monoclonal Antibody
GTR10419718Rabbit Tenascin X ELISA kit
NBP3-25332Rabbit Polyclonal Tenascin X Antibody
APRab18791-01Tenascin-X Rabbit Polyclonal Antibody
E47M60611Tenascin X Recombinant Rabbit mAb
SLM-60611R-01Rabbit Anti-Tenascin X antibody
GTR18711852Tenascin X Recombinant Rabbit mAb Antibody
NBP3-21427FRabbit Polyclonal Tenascin X Antibody [FITC]

Popular Products