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Mlx rabbit pAb

CAT: 0855-ES7353-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES7353-02Size:100 µL
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Background
The product of this gene belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. These factors form heterodimers with Mad proteins and play a role in proliferation, determination and differentiation. This gene product may act to diversify Mad family function by its restricted association with a subset of the Mad family of transcriptional repressors, namely, Mad1 and Mad4. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Description
The product of this gene belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. These factors form heterodimers with Mad proteins and play a role in proliferation, determination and differentiation. This gene product may act to diversify Mad family function by its restricted association with a subset of the Mad family of transcriptional repressors, namely, Mad1 and Mad4. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],
UniProt
Q9UH92
Swiss Prot
Q9UH92
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Mlx. AA range:111-160
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
33kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
33kD
Fragment
IgG
Subcellular Location
[Isoform Alpha]: Cytoplasm . Found predominantly in the cytoplasm (PubMed:10918583) . .; [Isoform Beta]: Cytoplasm . Found predominantly in the cytoplasm (PubMed:10918583) . .; [Isoform Gamma]: Nucleus . Found predominantly in the nucleus (PubMed:10918583) . .
Other Product Names
MLX; BHLHD13; TCFL4; Max-like protein X; Class D basic helix-loop-helix protein 13; bHLHd13; Max-like bHLHZip protein; Protein BigMax; Transcription factor-like protein 4
Gene ID (Human)
6945

UniProtKB · Q9UH92

Max-like protein X

MLX_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UH92
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MLX
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K2J3, B2RAV8, B2RD73, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3
Protein keywords

Molecular function

ActivatorDNA-bindingRepressor

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

Biological process

TranscriptionTranscription regulation

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