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RBQ-3 rabbit pAb

CAT: 0855-ES7008-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES7008-01Size:50 µL
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Background
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2010]
Description
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2010],
Product Name Alternative
RBBP5; RBQ3; Retinoblastoma-binding protein 5; RBBP-5; Retinoblastoma-binding protein RBQ-3
UniProt
Q15291
Swiss Prot
Q15291
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from RBQ-3 . at AA range: 190-270
Target
RBQ-3
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Buffer
-20°C/1 year
Molecular Weight
59kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
59kD
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
RBBP5; RBQ3; Retinoblastoma-binding protein 5; RBBP-5; Retinoblastoma-binding protein RBQ-3
Gene ID (Human)
5929