Products for Research Use Only
RegisterLogin

RARα rabbit pAb

CAT: 0855-ES6992-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES6992-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.[provided by RefSeq, Sep 2010]
Description
This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus. [provided by RefSeq, Sep 2010],
UniProt
P10276
Swiss Prot
P10276
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Retinoic Acid Receptor alpha. AA range:46-95
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
51kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
51kD
Fragment
IgG
Subcellular Location
Nucleus . Cytoplasm . Nuclear localization depends on ligand binding, phosphorylation and sumoylation (PubMed:19850744) . Translocation to the nucleus in the absence of ligand is dependent on activation of PKC and the downstream MAPK phosphorylation (By similarity) . Increased nuclear localization upon pulsatile shear stress (PubMed:28167758) . .
Other Product Names
RARA; NR1B1; Retinoic acid receptor alpha; RAR-alpha; Nuclear receptor subfamily 1 group B member 1
Gene ID (Human)
5914

Related Products

CatalogName
ES6991-01RARα (phospho Ser77) rabbit pAb
ES11179-01RARG rabbit pAb
ES4666-01RAB3IP rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb
ES20703-01JAK2 Rabbit rabbit pAb
ES20758-01ERK1 Rabbit rabbit pAb
ES20830-01ATG14L Rabbit rabbit pAb
ES20829-01ATG4a Rabbit rabbit pAb
ES20658-01NM23A Rabbit rabbit pAb
ES20826-01ATG5 Rabbit rabbit pAb

Alternative Products

CatalogName
A7420RARα Rabbit pAb
A1603RARβ Rabbit pAb
E45R12776NRARα Rabbit mAb
E45R13136N-100RARβ Rabbit mAb
APR29918N-01RARα Rabbit pAb (APR29918N)
APRab16903-01RARα Rabbit Polyclonal Antibody
APR22615N-01RARβ Rabbit pAb (APR22615N)
APR17430N-01RARα Rabbit pAb (APR17430N)
E47R0251RAR alpha Rabbit pAb
NGO-IB02301-032PPANEL of (h) RAR Reporter Assays: RARα, RARβ, & RARγ

Popular Products