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MARCH4 rabbit pAb

CAT: 0855-ES6921-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES6921-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19) . MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]) .[supplied by OMIM, Apr 2010]
Description
MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6. 3. 2. 19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment (Bartee et al. 2004 [PubMed 14722266]). [supplied by OMIM, Apr 2010],
UniProt
Q9P2E8
Swiss Prot
Q9P2E8
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human MARCH4. AA range:301-350
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Golgi apparatus membrane ; Multi-pass membrane protein .
Other Product Names
MARCH4; KIAA1399; RNF174; E3 ubiquitin-protein ligase MARCH4; Membrane-associated RING finger protein 4; Membrane-associated RING-CH protein IV; MARCH-IV; RING finger protein 174
Gene ID (Human)
57574