MARCH5 rabbit pAb

CAT: 0855-ES6673-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES6673-01Size:50 µL
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Background
MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2; MIM 608507) and DRP1 (DNM1L; MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]) .[supplied by OMIM, Mar 2008]
Description
MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2; MIM 608507) and DRP1 (DNM1L; MIM 603850) (Nakamura et al. 2006 [PubMed 16936636]). [supplied by OMIM, Mar 2008],
UniProt
Q9NX47
Swiss Prot
Q9NX47
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human MARCH5. AA range:21-70
Clonality
Polyclonal
Source
Rabbit
Applications
IF; WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
37kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
37kD
Fragment
IgG
Subcellular Location
Mitochondrion outer membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Authors show that the protein can be detected in endoplasmic reticulum (PubMed:14722266) . Authors (PubMed:16874301) show its presence only in mitochondria (PubMed:16874301) . .
Other Product Names
MARCH5; RNF153; E3 ubiquitin-protein ligase MARCH5; Membrane-associated RING finger protein 5; Membrane-associated RING-CH protein V; MARCH-V; Mitochondrial ubiquitin ligase; MITOL; RING finger protein 153
Gene ID (Human)
54708

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