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ZIP4 rabbit pAb

CAT: 0855-ES6734-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES6734-02Size:100 µL
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Background
This gene encodes a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The encoded protein localizes to cell membranes and is required for zinc uptake in the intestine. Mutations in this gene result in acrodermatitis enteropathica. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]
Description
This gene encodes a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The encoded protein localizes to cell membranes and is required for zinc uptake in the intestine. Mutations in this gene result in acrodermatitis enteropathica. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013],
Product Name Alternative
SLC39A4; ZIP4; Zinc transporter ZIP4; Solute carrier family 39 member 4; Zrt- and Irt-like protein 4; ZIP-4
UniProt
Q6P5W5
Swiss Prot
Q6P5W5
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human SLC39A4. AA range:431-480
Target
ZIP4
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
68kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
68kD
Fragment
IgG
Subcellular Location
Cell membrane ; Multi-pass membrane protein . Recycling endosome membrane ; Multi-pass membrane protein . Colocalized with TFRC in the recycling endosomes. Cycles between endosomal compartments and the plasma membrane in response to zinc availability.
Other Product Names
SLC39A4; ZIP4; Zinc transporter ZIP4; Solute carrier family 39 member 4; Zrt- and Irt-like protein 4; ZIP-4
Gene ID (Human)
55630

UniProtKB · Q6P5W5

Zinc transporter ZIP4

S39A4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q6P5W5
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SLC39A4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q7L5S5, Q9H6T8, Q9NXC4
Protein keywords

Coding sequence diversity

Alternative splicing

Ligand

CadmiumMetal-bindingZinc

Cellular component

Cell membraneEndosomeMembrane

Disease

Disease variant

PTM

Disulfide bondGlycoproteinUbl conjugation

Biological process

Ion transportTransportZinc transport

Technical term

Proteomics identificationReference proteome

Domain

SignalTransmembraneTransmembrane helix

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