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Formic acid (ammonium)

CAT: 0804-HY-Y0488A-01Size: 50 gDry Ice: NoHazardous: No
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CAT#:0804-HY-Y0488A-01Size:50 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Formic acid ammonium is the ammonium salt form of formic acid, which is an endogenous metabolite. Formic acid ammonium activates the nitric oxide/cyclic guanosine monophosphate (NO/cGMP) signaling pathway in endothelial cells and inhibits calcium ion influx in vascular smooth muscle cells, resulting in vasomotor relaxation. Formic acid ammonium inhibits cytochrome C oxidase (CcO) and disrupts the electron transport chain, leading to ATP depletion. Formic acid ammonium can be used as a feed additive, which can lower the feed pH value, inhibit the growth of microorganisms (such as Escherichia coli, Salmonella), and extend the shelf life of the feed[1][2][3].
CAS Number
540-69-2
Product Name Alternative
Ammonium formate
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
ATP Synthase; Bacterial; Calcium Channel; NO Synthase
Type
Natural Products
Related Pathways
Anti-infection; Immunology/Inflammation; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/formic-acid-ammonium-salt.html
Purity
98.51
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
[H]C(O[NH4])=O
Molecular Formula
CH5NO2
Molecular Weight
63.06
Precautions
H302, H315, H319, H335
References & Citations
[1]Eisemann JH, van Heugten E. Response of pigs to dietary inclusion of formic acid and ammonium formate. J Anim Sci. 2007 Jun;85 (6) :1530-9.|[2]Zhang Q, et al. Formic acid up-regulates vascular tension through nitric oxide-cGMP signaling pathway. Chem Biol Interact. 2019 Aug 25;309:108710. |[3]Kapur BM, Baber M. FASD: folic acid and formic acid - an unholy alliance in the alcohol abusing mother. Biochem Cell Biol. 2018 Apr;96 (2) :189-197.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature, keep dry and cool
Scientific Category
Natural Products
Clinical Information
No Development Reported
Citation 01
Phytomedicine. 2025 May:140:156619.|Cell Mol Life Sci. 2024 Nov 27;81 (1) :464.

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