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A-Raf (phospho Ser299) rabbit pAb

CAT: 0855-ES5954-01Size: 50 µLDry Ice: NoHazardous: No
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Background
This proto-oncogene belongs to the RAF subfamily of the Ser/Thr protein kinase family, and maybe involved in cell growth and development. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2012]
Description
This proto-oncogene belongs to the RAF subfamily of the Ser/Thr protein kinase family, and maybe involved in cell growth and development. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],
UniProt
P10398
Swiss Prot
P10398
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human A-RAF around the phosphorylation site of Ser299. AA range:266-315
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Intracellular, mitochondrion, cytosol
Other Product Names
ARAF; ARAF1; PKS; PKS2; Serine/threonine-protein kinase A-Raf; Proto-oncogene A-Raf; Proto-oncogene A-Raf-1; Proto-oncogene Pks
Gene ID (Human)
369

UniProtKB · P10398

Serine/threonine-protein kinase A-Raf

ARAF_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P10398
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ARAF
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1
Processing
—
Secondary accessions
P07557, Q5H9B2, Q5H9B3
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingMetal-bindingNucleotide-bindingZinc

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

PTM

Phosphoprotein

Disease

Proto-oncogene

Domain

Zinc-finger

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