Synaptotagmin X rabbit pAb

Synaptotagmin X rabbit pAb

• Description: Cofactor: Binds 3 calcium ions per subunit. The ions are bound to the C2 domains. function: May be involved in Ca (2+)-dependent exocytosis of secretory vesicles through Ca (2+) and phospholipid binding to the C2 domain or may serve as Ca (2+) sensors in the process of vesicular trafficking and exocytosis. similarity: Belongs to the synaptotagmin family. similarity: Contains 2 C2 domains. subunit: Homodimer. Can also form heterodimers. tissue specificity: Expressed only in pancreas, lung and kidney.
• Synonyms: SYT10; Synaptotagmin-10; Synaptotagmin X; SytX
• Gene ID: 341359
• UniProt: Q6XYQ8
• Cellular Locus: Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass membrane protein. Localizes to neuronal vesicles containing IGF1 that are not enriched at synapses. Does not colocalize with synaptic vesicles or with the Golgi apparatus..
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthesized peptide derived from Synaptotagmin X . at AA range: 380-460
• Clonality: Polyclonal
• Validated Applications: WB, IHC
• Stability: 1 year
• Concentration: 1 mg/mL
• Dilution: WB 1:500-2000;IHC-p 1:50-300
• Molecular Weight: 55kD
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.