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Synaptotagmin XI rabbit pAb

CAT: 0855-ES3534-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES3534-01Size:50 µL
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Background
Synaptotagmin 11 (SYT11) Homo sapiens This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature. [provided by RefSeq, Apr 2010]
Description
Synaptotagmin 11 (SYT11) Homo sapiens This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature. [provided by RefSeq, Apr 2010],
Product Name Alternative
SYT11; KIAA0080; Synaptotagmin-11; Synaptotagmin XI; SytXI
UniProt
Q9BT88
Swiss Prot
Q9BT88
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human SYT11. AA range:181-230
Target
Synaptotagmin XI
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
48kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
48kD
Fragment
IgG
Subcellular Location
Cytoplasmic vesicle membrane ; Single-pass membrane protein . Perikaryon . Golgi apparatus, trans-Golgi network membrane ; Single-pass membrane protein . Recycling endosome membrane ; Single-pass membrane protein . Lysosome membrane ; Single-pass membrane protein . Cytoplasmic vesicle, phagosome . Cell projection, axon . Cell projection, dendrite . Cell junction, synapse, postsynaptic density . Recycling endosome membrane ; Single-pass membrane protein . Cytoplasmic vesicle, clathrin-coated vesicle membrane ; Single-pass membrane protein . Perikaryon . Localized in vesicles that travels in axonal and dendritic shafts in both anterograde and retrograde directions. In macrophages and microglia, recruited in phagosomes at early stages of phagocytosis (By similarity) . Found in the core of the
Other Product Names
SYT11; KIAA0080; Synaptotagmin-11; Synaptotagmin XI; SytXI
Gene ID (Human)
23208

UniProtKB · Q9BT88

Synaptotagmin-11

SYT11_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9BT88
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SYT11
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q14998, Q5W0D4, Q68CT5, Q8IXU3, Q96SU2
Protein keywords

Ligand

CalciumMetal-binding

Cellular component

Cell projectionCytoplasmic vesicleEndosomeGolgi apparatusLysosomeMembraneSynapse

PTM

PhosphoproteinUbl conjugation

Technical term

Proteomics identificationReference proteome

Domain

RepeatTransmembraneTransmembrane helix

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