Synaptotagmin XI rabbit pAb

Synaptotagmin XI rabbit pAb

• Description: Synaptotagmin 11 (SYT11) Homo sapiens This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature. [provided by RefSeq, Apr 2010],
• Synonyms: SYT11; KIAA0080; Synaptotagmin-11; Synaptotagmin XI; SytXI
• Gene ID: 23208
• UniProt: Q9BT88
• Cellular Locus: Cytoplasmic vesicle membrane ; Single-pass membrane protein. Perikaryon. Golgi apparatus, trans-Golgi network membrane ; Single-pass membrane protein. Recycling endosome membrane ; Single-pass membrane protein. Lysosome membrane ; Single-pass membrane protein. Cytoplasmic vesicle, phagosome. Cell projection, axon. Cell projection, dendrite. Cell junction, synapse, postsynaptic density. Recycling endosome membrane ; Single-pass membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane ; Single-pass membrane protein. Perikaryon. Localized in vesicles that travels in axonal and dendritic shafts in both anterograde and retrograde directions. In macrophages and microglia, recruited in phagosomes at early stages of phagocytosis (By similarity). Found in the core of the
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human SYT11. AA range:181-230
• Clonality: Polyclonal
• Validated Applications: WB, ELISA
• Stability: 1 year
• Concentration: 1 mg/mL
• Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
• Molecular Weight: 48kD
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.