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TFIIIA rabbit pAb

CAT: 0855-ES5690-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES5690-01Size:50 µL
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Background
The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq, Jul 2008]
Description
The product of this gene is a Zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq, Jul 2008],
Product Name Alternative
GTF3A; Transcription factor IIIA; TFIIIA
UniProt
Q92664
Swiss Prot
Q92664
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from the Internal region of human TFIIIA.
Target
TFIIIA
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
41kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
41kD
Fragment
IgG
Subcellular Location
Nucleus.
Other Product Names
GTF3A; Transcription factor IIIA; TFIIIA
Gene ID (Human)
2971

UniProtKB · Q92664

Transcription factor IIIA

TF3A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q92664
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GTF3A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
TFIIIA
EC number
—
Processing
—
Secondary accessions
B7ZBK5, Q12963, Q13097
Protein keywords

Coding sequence diversity

Alternative splicing

Molecular function

DNA-bindingRNA-binding

Ligand

Metal-bindingZinc

Cellular component

Nucleus

Technical term

Proteomics identificationReference proteome

Domain

RepeatZinc-finger

Biological process

Ribosome biogenesisTranscriptionTranscription regulation