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Dkk-3 rabbit pAb

CAT: 0855-ES5541-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES5541-01Size:50 µL
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Background
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Description
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],
Product Name Alternative
DKK3; REIC; Dickkopf-related protein 3; Dickkopf-3; Dkk-3; hDkk-3
UniProt
Q9UBP4
Swiss Prot
Q9UBP4
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human DKK3. AA range:111-160
Target
Dkk-3
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
45kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
45kD
Fragment
IgG
Subcellular Location
Secreted.
Other Product Names
DKK3; REIC; Dickkopf-related protein 3; Dickkopf-3; Dkk-3; hDkk-3
Gene ID (Human)
27122

UniProtKB · Q9UBP4

Dickkopf-related protein 3

DKK3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UBP4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DKK3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Dickkopf-3, Dkk-3, hDkk-3
EC number
—
Processing
Precursor
Secondary accessions
A8K1I2, D3DQW1, Q9ULB7
Protein keywords

Domain

Coiled coilSignal

Molecular function

Developmental protein

Technical term

Direct protein sequencingProteomics identificationReference proteome

PTM

Disulfide bondGlycoprotein

Cellular component

Secreted

Biological process

Wnt signaling pathway

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