NOC2L rabbit pAb

• Background:

  NOC2 like nucleolar associated transcriptional repressor (NOC2L) Homo sapiens Histone modification by histone acetyltransferases (HAT) and histone deacetylases (HDAC) can control major aspects of transcriptional regulation. NOC2L represents a novel HDAC-independent inhibitor of histone acetyltransferase (INHAT) (Hublitz et al., 2005 [PubMed 16322561]) .[supplied by OMIM, Mar 2008]

• Description:

  NOC2 like nucleolar associated transcriptional repressor (NOC2L) Homo sapiens Histone modification by histone acetyltransferases (HAT) and histone deacetylases (HDAC) can control major aspects of transcriptional regulation. NOC2L represents a novel HDAC-independent inhibitor of histone acetyltransferase (INHAT) (Hublitz et al. 2005 [PubMed 16322561]). [supplied by OMIM, Mar 2008],

• UniProt:

  Q9Y3T9

• Swiss Prot:

  Q9Y3T9

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human NOC2L. AA range:602-651

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; IHC; IF; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

• Molecular Weight:

  85kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  85kD

• Fragment:

  IgG

• Subcellular Location:

  Nucleus, nucleoplasm. Nucleus, nucleolus. Translocates from the nucleoli to the nucleoplasm in presence of several stressors like ultraviolet irradiation and actinomycin-D. Predominantly detected in the nucleoli in non-mitotic cells. Predominantly detected in nucleoplasma in cells undergoing mitosis.

• Other Product Names:

  NOC2L; NIR; Nucleolar complex protein 2 homolog; Protein NOC2 homolog; NOC2-like protein; Novel INHAT repressor

• Gene ID (Human):

  26155