V-ATPase C2 rabbit pAb

V-ATPase C2 rabbit pAb

• Description: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms. [provided by RefSeq, Jul 2008],
• Synonyms: ATP6V1C2; V-type proton ATPase subunit C 2; V-ATPase subunit C 2; Vacuolar proton pump subunit C 2
• Gene ID: 245973
• UniProt: Q8NEY4
• Cellular Locus: Vacuolar proton-transporting V-type ATPase, V1 domain,lysosomal membrane,cytosol,proton-transporting V-type ATPase, V1 domain,extracellular exosome,
• Host: Rabbit
• Species Reactivity: Human, Rat, Mouse,
• Immunogen: The antiserum was produced against synthesized peptide derived from human ATP6V1C2. AA range:121-170
• Clonality: Polyclonal
• Validated Applications: WB, ELISA
• Stability: 1 year
• Concentration: 1 mg/mL
• Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
• Molecular Weight: 48kD
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.