V-ATPase H rabbit pAb

CAT: 0855-ES3689-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0855-ES3689-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. The encoded protein is the regulatory H subunit of the V1 domain of V-ATPase, which is required for catalysis of ATP but not the assembly of V-ATPase. Decreased expression of this gene may play a role in the development of type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]

Description

UniProt

Q9UI12

Swiss Prot

Q9UI12

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human ATP6V1H. AA range:341-390

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight

55kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

55kD

Fragment

IgG

Subcellular Location

Cytoplasmic vesicle, clathrin-coated vesicle membrane ; Peripheral membrane protein .

Other Product Names

ATP6V1H; CGI-11; V-type proton ATPase subunit H; V-ATPase subunit H; Nef-binding protein 1; NBP1; Protein VMA13 homolog; V-ATPase 50/57 kDa subunits; Vacuolar proton pump subunit H; Vacuolar proton pump subunit SFD

Gene ID (Human)

51606

UniProtKB · Q9UI12

V-type proton ATPase subunit H

VATH_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q9UI12
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: ATP6V1H
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: V-ATPase subunit H
EC number: —
Processing: —
Secondary accessions: B3KMR0, Q6PK44, Q9H3E3, Q9Y300

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cytoplasmic vesicleMembrane

Biological process

Host-virus interactionHydrogen ion transportIon transportTransport

PTM

Phosphoprotein

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Alternative Products

Catalog	Name
MBS8540730-01	V-ATPase D1 Rabbit pAb
MBS8541120-01	V-ATPase S1 Rabbit pAb
APRab19737-01	V-ATPase H Rabbit Polyclonal Antibody
APRab19733-01	V-ATPase B1 Rabbit Polyclonal Antibody
GTR18053244-01	V-ATPase S1 rabbit pAb Antibody
GTR18052477-01	V-ATPase D rabbit pAb Antibody
GTR18307047	V-ATPase C2 Rabbit Polyclonal Antibody
E28PT6079	V-ATPase S1 Rabbit Polyclonal Antibody
E53P06199	V-ATPase D1 Rabbit Polyclonal Antibody
APRab19735-01	V-ATPase D Rabbit Polyclonal Antibody