Cdc42EP4 rabbit pAb

• Background:

  The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control. [provided by RefSeq, Jul 2008]

• Description:

  The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control. [provided by RefSeq, Jul 2008],

• Synonyms:

  CDC42EP4; BORG4; CEP4; Cdc42 effector protein 4; Binder of Rho GTPases 4

• Gene ID:

  23580

• UniProt:

  Q9H3Q1

• Cellular Locus:

  Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton.

• Host:

  Rabbit

• Species Reactivity:

  Human, Rat, Mouse,

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human BORG4. AA range:201-250

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, IHC, IF, ELISA

• Validated Applications:

  WB, IHC, IF, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

• Molecular Weight:

  36kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  36 kD

• Subcellular Location:

  Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton.

• Other Product Names:

  CDC42EP4; BORG4; CEP4; Cdc42 effector protein 4; Binder of Rho GTPases 4

• Gene ID (Human):

  23580

• SwissProt (Human):

  Q9H3Q1