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Raftlin rabbit pAb

CAT: 0855-ES5314-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES5314-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:May play a pivotal role in the formation and/or maintenance of lipid rafts. May regulate B-cell antigen receptor-mediated signaling., similarity:Belongs to the raftlin family., subcellular location:Associates with lipid rafts., tissue specificity:Specifically expressed by B-cells (at protein level) .
Description
Function: May play a pivotal role in the formation and/or maintenance of lipid rafts. May regulate B-cell antigen receptor-mediated signaling. similarity: Belongs to the raftlin family. subcellular location: Associates with lipid rafts. tissue specificity: Specifically expressed by B-cells (at protein level).
Product Name Alternative
RFTN1; KIAA0084; MIG2; Raftlin; Cell migration-inducing gene 2 protein; Raft-linking protein
UniProt
Q14699
Swiss Prot
Q14699
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human RFTN1. AA range:432-481
Target
Raftlin
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Buffer
-20°C/1 year
Molecular Weight
65kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
65kD
Fragment
IgG
Subcellular Location
Cell membrane ; Lipid-anchor . Cytoplasm . Membrane raft . Endosome . Early endosome . Translocates from cytoplasm to cell membrane where it colocalizes with poly (I:C) and then moves to endosomes where it colocalizes with TLR3 (PubMed:21266579) . Translocates from cytoplasm to cell membrane where it colocalizes with TLR4 and then together with TLR4 moves to endosomes, upon lipopolysaccharide stimulation (PubMed:27022195) . .
Other Product Names
RFTN1; KIAA0084; MIG2; Raftlin; Cell migration-inducing gene 2 protein; Raft-linking protein
Gene ID (Human)
23180

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