Products for Research Use Only
RegisterLogin

APLF rabbit pAb

CAT: 0855-ES5104-02Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES5104-02Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks (Iles et al., 2007 [PubMed 17353262]) .[supplied by OMIM, Mar 2008]
Description
C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks (Iles et al. 2007 [PubMed 17353262]). [supplied by OMIM, Mar 2008],
UniProt
Q8IW19
Swiss Prot
Q8IW19
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human APLF. AA range:82-131
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
57kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
57kD
Fragment
IgG
Subcellular Location
Nucleus . Chromosome . Cytoplasm, cytosol . Localizes to DNA damage sites (PubMed:18474613, PubMed:18172500, PubMed:21211721, PubMed:23689425) . Accumulates at single-strand breaks and double-strand breaks via the PBZ-type zinc fingers (PubMed:18172500) . .
Other Product Names
APLF; C2orf13; PALF; XIP1; Aprataxin and PNK-like factor; Apurinic-apyrimidinic endonuclease APLF; PNK and APTX-like FHA domain-containing protein; XRCC1-interacting protein 1
Gene ID (Human)
200558

UniProtKB · Q8IW19

Aprataxin and PNK-like factor

APLF_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8IW19
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
APLF
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.1.-.-
Processing
—
Secondary accessions
A8K476, Q53P47, Q53PB9, Q53QU0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

ADP-ribosylationPhosphoprotein

Cellular component

ChromosomeCytoplasmNucleus

Domain

Coiled coilRepeatZinc-finger

Biological process

DNA damageDNA repair

Molecular function

Hydrolase

Ligand

Metal-bindingNucleotide-bindingZinc

Related Products

CatalogName
ES5103-01APLF (phospho Ser116) rabbit pAb
ES8910-01APLF Rabbit Polyclonal Antibody
ES1679-01APLP-2 rabbit pAb
ES3788-01APLP-1 rabbit pAb
ES4666-01RAB3IP rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb
ES20703-01JAK2 Rabbit rabbit pAb
ES20758-01ERK1 Rabbit rabbit pAb
ES20830-01ATG14L Rabbit rabbit pAb
ES20829-01ATG4a Rabbit rabbit pAb

Alternative Products

CatalogName
A17842-01APLF Rabbit pAb
NBP1-86806Rabbit Polyclonal APLF Antibody
TA362845APLF Rabbit Polyclonal Antibody
APR29633N-01APLF Rabbit pAb (APR29633N)
SL12489R-01Rabbit Anti-APLF antibody
520142-01APLF

Popular Products