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EIF4B rabbit pAb

CAT: 0855-ES5075-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES5075-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F., similarity:Contains 1 RRM (RNA recognition motif) domain., subunit:Self-associates and interacts with EIF3 p170 subunit.
Description
Function: Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F. similarity: Contains 1 RRM (RNA recognition motif) domain. subunit: Self-associates and interacts with EIF3 p170 subunit.
Product Name Alternative
EIF4B; Eukaryotic translation initiation factor 4B; eIF-4B
UniProt
P23588
Swiss Prot
P23588
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human eIF4B. AA range:388-437
Target
EIF4B
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
70kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
70kD
Fragment
IgG
Subcellular Location
Cytosol, polysome, eukaryotic translation initiation factor 4F complex, dendrite, neuronal cell body
Other Product Names
EIF4B; Eukaryotic translation initiation factor 4B; eIF-4B
Gene ID (Human)
1975

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