eIF4B rabbit pAb
CAT:
855-ES5075-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
eIF4B rabbit pAb
- Description: Function: Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F. similarity: Contains 1 RRM (RNA recognition motif) domain. subunit: Self-associates and interacts with EIF3 p170 subunit.
- Synonyms: EIF4B; Eukaryotic translation initiation factor 4B; eIF-4B
- Gene ID: 1975
- UniProt: P23588
- Cellular Locus: Cytosol,polysome,eukaryotic translation initiation factor 4F complex,dendrite,neuronal cell body,
- Host: Rabbit
- Species Reactivity: Human, Mouse
- Immunogen: The antiserum was produced against synthesized peptide derived from human eIF4B. AA range:388-437
- Clonality: Polyclonal
- Validated Applications: WB, IHC, IF, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
- Molecular Weight: 70kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.