DGK-θ rabbit pAb
CAT:
855-ES4961-02
Size:
100 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
DGK-θ rabbit pAb
- Description: The protein encoded by this gene contains three cysteine-rich domains, a proline-rich region, and a pleckstrin homology domain with an overlapping Ras-associating domain. It is localized in the speckle domains of the nucleus, and mediates the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. [provided by RefSeq, Jul 2008],
- Synonyms: DGKQ; DAGK4; Diacylglycerol kinase theta; DAG kinase theta; Diglyceride kinase theta; DGK-theta
- Gene ID: 1609
- UniProt: P52824
- Cellular Locus: Cytoplasm. Cytoplasm, cytosol. Cell membrane. Cell junction, synapse. Cytoplasm, cytoskeleton. Nucleus. Nucleus speckle. Nucleus matrix. Translocates to the plasma membrane in response to steroid hormone receptor stimulation (PubMed:15632189). Translocation to the plasma membrane is dependent on G-protein coupled receptor stimulation and subsequent activation of PRKCE and probably PRKCH (PubMed:15632189). Translocates to the nucleus in response to thrombin stimulation (Probable). Association with the nuclear matrix is regulated by nerve growth factor (By similarity)..
- Host: Rabbit
- Species Reactivity: Human, Rat, Mouse,
- Immunogen: The antiserum was produced against synthesized peptide derived from human DGKQ. AA range:691-740
- Clonality: Polyclonal
- Validated Applications: WB, IHC, IF, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
- Molecular Weight: 101kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.