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Pragmin (phospho Tyr413) rabbit pAb

CAT: 0855-ES4942-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES4942-01Size:50 µL
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Background
This gene encodes an enzyme that belongs to the tyrosine protein kinase family. A similar protein in rat binds to Rho family GTPase 2 (Rnd2) and regulates neurite outgrowth via activation of Ras homolog gene family, member A (RhoA) . [provided by RefSeq, Mar 2014]
Description
This gene encodes an enzyme that belongs to the tyrosine protein kinase family. A similar protein in rat binds to Rho family GTPase 2 (Rnd2) and regulates neurite outgrowth via activation of Ras homolog gene family, member A (RhoA). [provided by RefSeq, Mar 2014],
UniProt
Q86YV5
Swiss Prot
Q86YV5
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human Pragmin (phospho Tyr413)
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
175kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
175kD
Fragment
IgG
Subcellular Location
Cytoplasm . Cell junction, focal adhesion . Nucleus . Colocalized with NOTCH1 in the nucleus. .
Other Product Names
SGK223; Tyrosine-protein kinase SgK223; Sugen kinase 223
Gene ID (Human)
157285

UniProtKB · Q86YV5

Inactive tyrosine-protein kinase PRAG1

PRAG1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q86YV5
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PRAG1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q8N3N5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Cell junctionCytoplasmNucleus

PTM

Phosphoprotein

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