Pragmin (phospho Tyr413) rabbit pAb

• Background:

  This gene encodes an enzyme that belongs to the tyrosine protein kinase family. A similar protein in rat binds to Rho family GTPase 2 (Rnd2) and regulates neurite outgrowth via activation of Ras homolog gene family, member A (RhoA) . [provided by RefSeq, Mar 2014]

• Description:

  This gene encodes an enzyme that belongs to the tyrosine protein kinase family. A similar protein in rat binds to Rho family GTPase 2 (Rnd2) and regulates neurite outgrowth via activation of Ras homolog gene family, member A (RhoA). [provided by RefSeq, Mar 2014],

• Synonyms:

  SGK223; Tyrosine-protein kinase SgK223; Sugen kinase 223

• Gene ID:

  157285

• UniProt:

  Q86YV5

• Cellular Locus:

  Cytoplasm. Cell junction, focal adhesion. Nucleus. Colocalized with NOTCH1 in the nucleus..

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Synthesized phospho-peptide around the phosphorylation site of human Pragmin (phospho Tyr413)

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, IHC, IF, ELISA

• Validated Applications:

  WB, IHC, IF, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

• Molecular Weight:

  175kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  175 kD

• Subcellular Location:

  Cytoplasm . Cell junction, focal adhesion . Nucleus . Colocalized with NOTCH1 in the nucleus. .

• Other Product Names:

  SGK223; Tyrosine-protein kinase SgK223; Sugen kinase 223

• Gene ID (Human):

  157285

• SwissProt (Human):

  Q86YV5