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PARP-4 rabbit pAb

CAT: 0855-ES4835-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES4835-01Size:50 µL
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Background
This gene encodes poly (ADP-ribosyl) transferase-like 1 protein, which is capable of catalyzing a poly (ADP-ribosyl) ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus. [provided by RefSeq, Jul 2008]
Description
This gene encodes poly (ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly (ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus. [provided by RefSeq, Jul 2008],
UniProt
Q9UKK3
Swiss Prot
Q9UKK3
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human PARP4. AA range:1151-1200
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, spindle . Also found in the nucleus, associated with mitotic spindles. .
Other Product Names
PARP4; ADPRTL1; KIAA0177; PARPL; Poly [ADP-ribose] polymerase 4; PARP-4; 193 kDa vault protein; ADP-ribosyltransferase diphtheria toxin-like 4; ARTD4; PARP-related/IalphaI-related H5/proline-rich; PH5P; Vault poly (ADP-ribose) polymerase; VP
Gene ID (Human)
143

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