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CREM rabbit pAb

CAT: 0855-ES4813-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES4813-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CAMP responsive element modulator (CREM) Homo sapiens This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. [provided by RefSeq, Jul 2008]
Description
CAMP responsive element modulator (CREM) Homo sapiens This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. [provided by RefSeq, Jul 2008],
UniProt
Q03060
Swiss Prot
Q03060
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human CREM. AA range:81-130
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
34kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
34kD
Fragment
IgG
Subcellular Location
Nucleus.; [Isoform 6]: Cytoplasm . Nucleus .
Other Product Names
CREM; cAMP-responsive element modulator; Inducible cAMP early repressor; ICER
Gene ID (Human)
1390

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