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CLN5 rabbit pAb

CAT: 0855-ES4682-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES4682-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Ceroid-lipofuscinosis, neuronal 5 (CLN5) Homo sapiens This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL) . Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.[provided by RefSeq, Oct 2008]
Description
Ceroid-lipofuscinosis, neuronal 5 (CLN5) Homo sapiens This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function. [provided by RefSeq, Oct 2008],
Product Name Alternative
CLN5; Ceroid-lipofuscinosis neuronal protein 5; Protein CLN5
UniProt
O75503
Swiss Prot
O75503
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human CLN5. AA range:171-220
Target
CLN5
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
48kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
48kD
Fragment
IgG
Subcellular Location
[Ceroid-lipofuscinosis neuronal protein 5, secreted form]: Lysosome .; [Ceroid-lipofuscinosis neuronal protein 5]: Membrane ; Single-pass type II membrane protein . An amphipathic anchor region facilitates its association with the membrane. .
Other Product Names
CLN5; Ceroid-lipofuscinosis neuronal protein 5; Protein CLN5
Gene ID (Human)
1203

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