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VPS26B rabbit pAb

CAT: 0855-ES4632-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES4632-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the VPS26 family., subcellular location:Does not localize to endosomes., subunit:Probable component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. Interacts directly with VPS35.
Description
Function: Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Belongs to the VPS26 family. subcellular location: Does not localize to endosomes. subunit: Probable component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. Interacts directly with VPS35.
Product Name Alternative
VPS26B; Vacuolar protein sorting-associated protein 26B; Vesicle protein sorting 26B
UniProt
Q4G0F5
Swiss Prot
Q4G0F5
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human VPS26B. AA range:231-280
Target
VPS26B
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
45kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
45kD
Fragment
IgG
Subcellular Location
Cytoplasm . Membrane; Peripheral membrane protein . Early endosome . Late endosome . Localizes to early and late endosomal structures (By similarity) . .
Other Product Names
VPS26B; Vacuolar protein sorting-associated protein 26B; Vesicle protein sorting 26B
Gene ID (Human)
112936

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