USP19 rabbit pAb

• Background:

  Catalytic activity:Ubiquitin C-terminal thioester + H (2) O = ubiquitin + a thiol., function:Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., sequence caution:Translation N-terminally shortened., similarity:Belongs to the peptidase C19 family., similarity:Contains 1 MYND-type zinc finger., similarity:Contains 2 CS domains.

• Description:

  Catalytic activity: Ubiquitin C-terminal thioester + H (2)O = ubiquitin + a thiol. function: Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. sequence Caution: Translation N-terminally shortened. similarity: Belongs to the peptidase C19 family. similarity: Contains 1 MYND-type zinc finger. similarity: Contains 2 CS domains.

• Synonyms:

  USP19; KIAA0891; ZMYND9; Ubiquitin carboxyl-terminal hydrolase 19; Deubiquitinating enzyme 19; Ubiquitin thioesterase 19; Ubiquitin-specific-processing protease 19; Zinc finger MYND domain-containing protein 9

• Gene ID:

  10869

• UniProt:

  O94966

• Cellular Locus:

  Endoplasmic reticulum membrane ; Single-pass membrane protein.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human USP19. AA range:391-440

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB; IHC; IF; ELISA

• Validated Applications:

  WB, IHC, IF, ELISA

• Stability:

  -20°C / 1 year

• Concentration:

  1 mg/mL

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

• Molecular Weight:

  130kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  130kD

• Subcellular Location:

  Endoplasmic reticulum membrane ; Single-pass membrane protein .

• Other Product Names:

  USP19; KIAA0891; ZMYND9; Ubiquitin carboxyl-terminal hydrolase 19; Deubiquitinating enzyme 19; Ubiquitin thioesterase 19; Ubiquitin-specific-processing protease 19; Zinc finger MYND domain-containing protein 9

• Gene ID (Human):

  10869

• SwissProt (Human):

  O94966