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Epac rabbit pAb

CAT: 0855-ES4469-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES4469-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Caution:It is uncertain whether Met-1 or Met-43 is the initiator., domain:The DEP domain is involved in membrane localization independent from regulation by cAMP., function:Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP., similarity:Contains 1 cyclic nucleotide-binding domain., similarity:Contains 1 DEP domain., similarity:Contains 1 N-terminal Ras-GEF domain., similarity:Contains 1 Ras-GEF domain., tissue specificity:Widely expressed with highest levels in adult kidney, heart, thyroid and brain, and fetal kidney.
Description
Caution: It is uncertain whether Met-1 or Met-43 is the initiator. Domain: The DEP domain is involved in membrane localization independent from regulation by cAMP. function: Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. similarity: Contains 1 cyclic nucleotide-binding domain. similarity: Contains 1 DEP domain. similarity: Contains 1 N-terminal Ras-GEF domain. similarity: Contains 1 Ras-GEF domain. tissue specificity: Widely expressed with highest levels in adult kidney, heart, thyroid and brain, and fetal kidney.
Product Name Alternative
RAPGEF3; CGEF1; EPAC; EPAC1; Rap guanine nucleotide exchange factor 3; Exchange factor directly activated by cAMP 1; Exchange protein directly activated by cAMP 1; EPAC 1; Rap1 guanine-nucleotide-exchange factor directly activated by cAMP
UniProt
O95398
Swiss Prot
O95398
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human RAPGEF3. AA range:712-761
Target
Epac
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
100kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
100kD
Fragment
IgG
Subcellular Location
Endomembrane system .
Other Product Names
RAPGEF3; CGEF1; EPAC; EPAC1; Rap guanine nucleotide exchange factor 3; Exchange factor directly activated by cAMP 1; Exchange protein directly activated by cAMP 1; EPAC 1; Rap1 guanine-nucleotide-exchange factor directly activated by cAMP
Gene ID (Human)
10411

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