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DEF-3 rabbit pAb

CAT: 0855-ES4433-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES4433-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Disease:Defects in RBM6 are found in non-small cell lung cancer (NSCLC) cell lines., function:Specifically binds poly (G) RNA homopolymers in vitro., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 1 G-patch domain., similarity:Contains 1 RRM (RNA recognition motif) domain., tissue specificity:Ubiquitous in adults.
Description
Disease: Defects in RBM6 are found in non-small cell lung cancer (NSCLC) cell lines. function: Specifically binds poly (G) RNA homopolymers in vitro. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Contains 1 G-patch domain. similarity: Contains 1 RRM (RNA recognition motif) domain. tissue specificity: Ubiquitous in adults.
Product Name Alternative
RBM6; DEF3; RNA-binding protein 6; Lung cancer antigen NY-LU-12; Protein G16; RNA-binding motif protein 6; RNA-binding protein DEF-3
UniProt
P78332
Swiss Prot
P78332
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human RBM6. AA range:991-1040
Target
DEF3
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
150kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
150kD
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
RBM6; DEF3; RNA-binding protein 6; Lung cancer antigen NY-LU-12; Protein G16; RNA-binding motif protein 6; RNA-binding protein DEF-3
Gene ID (Human)
10180