DEF-3 rabbit pAb

• Background:

  Disease:Defects in RBM6 are found in non-small cell lung cancer (NSCLC) cell lines., function:Specifically binds poly (G) RNA homopolymers in vitro., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 1 G-patch domain., similarity:Contains 1 RRM (RNA recognition motif) domain., tissue specificity:Ubiquitous in adults.

• Description:

  Disease: Defects in RBM6 are found in non-small cell lung cancer (NSCLC) cell lines. function: Specifically binds poly (G) RNA homopolymers in vitro. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Contains 1 G-patch domain. similarity: Contains 1 RRM (RNA recognition motif) domain. tissue specificity: Ubiquitous in adults.

• Synonyms:

  RBM6; DEF3; RNA-binding protein 6; Lung cancer antigen NY-LU-12; Protein G16; RNA-binding motif protein 6; RNA-binding protein DEF-3

• Gene ID:

  10180

• UniProt:

  P78332

• Cellular Locus:

  Nucleus.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse

• Reactivity:

  Human; Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human RBM6. AA range:991-1040

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, IHC, IF, ELISA

• Validated Applications:

  WB, IHC, IF, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

• Molecular Weight:

  150kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  150 kD

• Subcellular Location:

  Nucleus .

• Other Product Names:

  RBM6; DEF3; RNA-binding protein 6; Lung cancer antigen NY-LU-12; Protein G16; RNA-binding motif protein 6; RNA-binding protein DEF-3

• Gene ID (Human):

  10180

• SwissProt (Human):

  P78332