CD155 rabbit pAb

• Background:

  The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

• Description:

  The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008],

• UniProt:

  P15151

• Swiss Prot:

  P15151

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from the Internal region of human PVR. AA range:81-130

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB IF; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications.

• Molecular Weight:

  70kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  70kD

• Fragment:

  IgG

• Subcellular Location:

  [Isoform Alpha]: Cell membrane; Single-pass type I membrane protein.; [Isoform Delta]: Cell membrane; Single-pass type I membrane protein.; [Isoform Beta]: Secreted.; [Isoform Gamma]: Secreted.

• Other Product Names:

  PVR; PVS; Poliovirus receptor; Nectin-like protein 5; NECL-5; CD155

• Gene ID (Human):

  5817