CD155 rabbit pAb

CAT: 0855-ES4358-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES4358-01Size:50 µL
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Background
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Description
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008],
Product Name Alternative
PVR; PVS; Poliovirus receptor; Nectin-like protein 5; NECL-5; CD155
UniProt
P15151
Swiss Prot
P15151
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human PVR. AA range:81-130
Target
CD155
Clonality
Polyclonal
Source
Rabbit
Applications
WB IF; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
70kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
70kD
Fragment
IgG
Subcellular Location
[Isoform Alpha]: Cell membrane; Single-pass type I membrane protein.; [Isoform Delta]: Cell membrane; Single-pass type I membrane protein.; [Isoform Beta]: Secreted.; [Isoform Gamma]: Secreted.
Other Product Names
PVR; PVS; Poliovirus receptor; Nectin-like protein 5; NECL-5; CD155
Gene ID (Human)
5817

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