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CD85f rabbit pAb

CAT: 0855-ES4195-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES4195-01Size:50 µL
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Background
The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Description
The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13. 4. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008],
Product Name Alternative
LILRA5; ILT11; LILRB7; LIR9; Leukocyte immunoglobulin-like receptor subfamily A member 5; CD85 antigen-like family member F; Immunoglobulin-like transcript 11; ILT-11; Leukocyte immunoglobulin-like receptor 9; LIR-9; CD85f
UniProt
A6NI73
Swiss Prot
A6NI73
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human LILRA5. AA range:141-190
Target
CD85f
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
33kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
33kD
Fragment
IgG
Subcellular Location
Cell membrane ; Single-pass type I membrane protein .; [Isoform 3]: Secreted .
Other Product Names
LILRA5; ILT11; LILRB7; LIR9; Leukocyte immunoglobulin-like receptor subfamily A member 5; CD85 antigen-like family member F; Immunoglobulin-like transcript 11; ILT-11; Leukocyte immunoglobulin-like receptor 9; LIR-9; CD85f
Gene ID (Human)
353514

UniProtKB · A6NI73

Leukocyte immunoglobulin-like receptor subfamily A member 5

LIRA5_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
A6NI73
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LILRA5
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A6NHI3
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembraneSecreted

PTM

Disulfide bondGlycoprotein

Biological process

ImmunityInnate immunity

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

Molecular function

Receptor

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