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MAPK Organizer 1 rabbit pAb

CAT: 0855-ES4175-01Size: 50 µLDry Ice: NoHazardous: No
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Background
This gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Description
This gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],
Product Name Alternative
WDR83; MORG1; WD repeat domain-containing protein 83; Mitogen-activated protein kinase organizer 1; MAPK organizer 1
UniProt
Q9BRX9
Swiss Prot
Q9BRX9
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human WDR83. AA range:141-190
Target
MAPK Organizer 1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
34kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
34kD
Fragment
IgG
Subcellular Location
Cytoplasm . Nucleus . Predominantly cytoplasmic. Partially nuclear. .
Other Product Names
WDR83; MORG1; WD repeat domain-containing protein 83; Mitogen-activated protein kinase organizer 1; MAPK organizer 1
Gene ID (Human)
84292

UniProtKB · Q9BRX9

WD repeat domain-containing protein 83

WDR83_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9BRX9
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
WDR83
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B2RAF1, Q53FT6
Protein keywords

Cellular component

CytoplasmLysosomeNucleusSpliceosome

Biological process

mRNA processingmRNA splicing

Technical term

Proteomics identificationReference proteome

Domain

RepeatWD repeat