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Inhibin β-A rabbit pAb

CAT: 0855-ES4139-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES4139-01Size:50 µL
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Background
This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. The encoded protein also plays a role in eye, tooth and testis development. Elevated expression of this gene may be associated with cancer cachexia in human patients. [provided by RefSeq, Aug 2016]
Description
This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. The encoded protein also plays a role in eye, tooth and testis development. Elevated expression of this gene may be associated with cancer cachexia in human patients. [provided by RefSeq, Aug 2016],
Product Name Alternative
INHBA; Inhibin beta A chain; Activin beta-A chain; Erythroid differentiation protein; EDF
UniProt
P08476
Swiss Prot
P08476
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the C-terminal region of human INHBA. AA range:377-426
Target
Inhibin β-A
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
52kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
52kD
Fragment
IgG
Subcellular Location
Secreted.
Other Product Names
INHBA; Inhibin beta A chain; Activin beta-A chain; Erythroid differentiation protein; EDF
Gene ID (Human)
3624

UniProtKB · P08476

Inhibin beta A chain

INHBA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P08476
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
INHBA
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q14599
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoprotein

Molecular function

Growth factorHormone

Cellular component

Secreted

Domain

Signal

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