Products for Research Use Only
RegisterLogin

Bag-1 rabbit pAb

CAT: 0855-ES4090-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES4090-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. [provided by RefSeq, Feb 2010]
Description
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. [provided by RefSeq, Feb 2010],
Product Name Alternative
BAG1; HAP; BAG family molecular chaperone regulator 1; BAG-1; Bcl-2-associated athanogene 1
UniProt
Q99933
Swiss Prot
Q99933
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human BAG1. AA range:41-90
Target
Bag-1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
35kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
35kD
Fragment
IgG
Subcellular Location
[Isoform 1]: Nucleus. Cytoplasm. Isoform 1 localizes predominantly to the nucleus.; [Isoform 2]: Cytoplasm. Nucleus. Isoform 2 localizes to the cytoplasm and shuttles into the nucleus in response to heat shock.; [Isoform 4]: Cytoplasm. Nucleus. Isoform 4 localizes predominantly to the cytoplasm. The cellular background in which it is expressed can influence whether it resides primarily in the cytoplasm or is also found in the nucleus. In the presence of BCL2, localizes to intracellular membranes (what appears to be the nuclear envelope and perinuclear membranes) as well as punctate cytosolic structures suggestive of mitochondria.
Other Product Names
BAG1; HAP; BAG family molecular chaperone regulator 1; BAG-1; Bcl-2-associated athanogene 1
Gene ID (Human)
573

Related Products

CatalogName
ES4274-01Bag-3 rabbit pAb
ES8054-01Bag-3 rabbit pAb
ES1745-01Bag-4 rabbit pAb
ES10803-01BAG2 rabbit pAb
ES4354-01SIRP-α1/β1 rabbit pAb
ES20692-01Kininogen 1 Rabbit rabbit pAb
EA313-01Kv11.1 Rabbit pAb
ES1718-01Ataxin-1 rabbit pAb
ES1577-01ACAT-1 rabbit pAb
ES4382-01IRF-1 rabbit pAb

Alternative Products

CatalogName
MBS8540853-01BAG-1 Rabbit pAb
NBP1-89547-25ulRabbit Polyclonal Bag-1 Antibody
APRab07434-01Bag-1 Rabbit Polyclonal Antibody
B2019572BAG-1 Rabbit Monoclonal Antibody
GTR18051442-01Bag-1 rabbit pAb Antibody
NBP3-22527-100ulRabbit Monoclonal Bag-1 Antibody (SR1542)
NBP2-77409Rabbit Monoclonal Bag-1 Antibody (RM310)
NBP2-77438Rabbit Monoclonal Bag-1 Antibody (RM356)
NBP3-32068Rabbit Monoclonal Bag-1 Antibody (JE63-22)
PA87117HU-01Rabbit Anti-Human Bag-1 Polyclonal Antibody

Popular Products