Fractalkine rabbit pAb
CAT:
855-ES4084-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Fractalkine rabbit pAb
- Description: Function: The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1. induction: By TNF and IL-1 in pulmonary endothelial cells and umbilical vein endothelial cells. online information: CX3CL1 entry, PTM: A soluble short 95 kDa form may be released by proteolytic cleavage from the long membrane-anchored form. similarity: Belongs to the intercrine delta family. subunit: Monomer. tissue specificity: Small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas.
- Synonyms: CX3CL1; FKN; NTT; SCYD1; A-152E5.2; Fractalkine; C-X3-C motif chemokine 1; CX3C membrane-anchored chemokine; Neurotactin; Small-inducible cytokine D1
- Gene ID: 6376
- UniProt: P78423
- Cellular Locus: Cell membrane ; Single-pass type I membrane protein.; [Processed fractalkine]: Secreted.
- Host: Rabbit
- Species Reactivity: Human, Rat, Mouse,
- Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CX3CL1. AA range:231-280
- Clonality: Polyclonal
- Validated Applications: WB, IHC, IF, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
- Molecular Weight: 42kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.